Jama cardiology.

This secondary analysis of a randomized clinical trial examines whether longitudinal increases in high-sensitivity C-reactive protein levels during 16 weeks after an acute coronary syndrome are associated with increased risk of a major adverse cardiac event, cardiovascular death, and all-cause... Mehta LS , Beckie TM , DeVon HA , et al; American Heart Association Cardiovascular Disease in Women and Special Populations Committee of the Council on Clinical Cardiology, Council on Epidemiology and Prevention, Council on Cardiovascular and Stroke Nursing, and Council on Quality of Care and Outcomes Research. Under the premise of sex-specific physiology, we calculated between-sex differences (women minus men) in the change of BP values from baseline, and these data demonstrate faster rates of increase in women than men for all BP measures, particularly for systolic BP and pulse pressure (PP). Fitted lines denote mean sex differences in incremental BP …Importance Primary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on risk stratification. Genome-wide polygenic risk scores (PRSs) are proposed to improve ASCVD risk estimation. Objective To determine whether genome-wide PRSs for coronary artery disease (CAD) and acute ischemic stroke improve ASCVD risk estimation with traditional clinical risk … This analysis of data from the 2016 Global Burden of Disease Study examines the national and province-level mortality, prevalence, and disability-adjusted life-years associated with cardiovascular disease in China from 1990 to 2016.

JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality.Piepoli MF , Hoes AW , Agewall S , et al; ESC Scientific Document Group. 2016 European guidelines on cardiovascular disease prevention in clinical practice: the Sixth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of …

JAMA Cardiology. Full Text. Abstract Importance Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity and mortality due to atherosclerotic cardiovascular disease. Familial hypercholesterolemia affects 1 in 200 to 250 people around the world of every race and ethnicity.Importance Computed tomography–derived fractional flow reserve (FFR-CT) is a novel, noninvasive test for myocardial ischemia. Clinicians using FFR-CT must be able to interpret individual FFR-CT results to determine subsequent patient care. Objective To provide clinicians a means of interpreting individual FFR-CT results with respect to the range of …

JAMA Cardiology. Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), ...Key Points. Question Are initial and serial increases in high-sensitivity C-reactive protein levels after acute coronary syndrome in medically optimized patients associated with increased risk of a major cardiac event, cardiovascular death, and all-cause death?. Findings In this secondary analysis of the VISTA-16 randomized clinical trial that …The 2018 American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Rhythm Society (HRS) Guideline on the Evaluation and Management of Patients with Bradycardia and Cardiac Conduction Delay offers guidance to clinicians for the treatment of adult patients with bradycardia or symptoms thought to be associated with bradycardia or cardiac conduction …Mar 6, 2024 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959)

Key Points. Question What are the trends in heart failure (HF)–related mortality in young adults?. Findings In this cohort study, 61 729 HF-related deaths were identified in young adults between 1999 and 2019, and the overall age-adjusted mortality rate per 100 000 persons increased from 2.36 in 1999 to 3.16 in 2019.

The JAMA Cardiology Patient Page is a public service of JAMA Cardiology. The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis. For specific information concerning your personal medical condition, JAMA Cardiology suggests that you consult your physician ...

JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) With aging, telomerase knockout mice hearts showed shortening of telomeres, attenuated proliferation and increased apoptosis of cardiomyocytes, and greater cardiac remodeling and left ventricular failure. 30,31 On the other hand, enhanced expression of telomerase reverse transcriptase in rat cardiomyocytes preserved …Key Points. Question Is patient sex associated with differences in clinical outcomes of pulsed field ablation (PFA) for the treatment of patients with atrial fibrillation (AF)?. Findings In this large cohort study using a patient-level registry including 1568 consecutive patients who underwent PFA for paroxysmal or persistent AF, there was no significant difference …Serum creatinine at enrollment before cardiac catheterization was obtained from routine clinic visits or hospitalizations within the Emory Healthcare system. The eGFR (milliliter per minute per 1.73 m 2 ) was computed using the Chronic Kidney Disease Epidemiology Collaboration equation. 16 Medications were obtained by self-report and …JAMA Cardiology. Key Points. Question When does the clinical benefit of dapagliflozin emerge in patients with heart failure with reduced ejection fraction, and what is the magnitude as a function of proximity to prior heart failure hospitalization?

JAMA Cardiology. Full Text. Abstract Importance Familial hypercholesterolemia (FH) is an underdiagnosed and undertreated genetic disorder that leads to premature morbidity and mortality due to atherosclerotic cardiovascular disease. Familial hypercholesterolemia affects 1 in 200 to 250 people around the world of every race and ethnicity. JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JAMA Cardiology. Home New Online Current Issue For Authors. Podcast. Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & …Disclaimer: Dr Mehran is Associate Editor of JAMA Cardiology, but she was not involved in any of the decisions regarding review of the manuscript or its acceptance. References 1. Kirchhof P , Benussi S , Kotecha D , et al; ESC Scientific Document Group. 2016 ESC guidelines for the management of atrial fibrillation developed in ...JAMA Cardiology. Country. United States. Universities and research institutions in United States. Media Ranking in United States. Subject Area and Category. …

Importance The role of the coronary venous circulation in regulating myocardial perfusion and its potential in treating microvascular angina is unexplored.. Objective To evaluate whether an increase in coronary venous pressure modifies microvascular resistance in patients with microvascular angina.. Design, Setting, and Participants This was a blinded, sham-controlled, …A, Overall survival of patients with DNMT3A or TET2 mutations with a VAF greater than 0.005 to 0.01; a VAF of at least 0.01 to 0.02; a VAF of at least 0.02; and non-CHIP patients reveals dose-response of clone size and clinical outcome; B, Event-free survival free of death or rehospitalization for heart failure with DNMT3A or TET2 mutations at various …

JAMA Cardiology. JAMA Guide to Statistics and Methods. Overlap Weighting—A Propensity Score Method That Mimics Attributes of a Randomized Clinical Trial. Laine E. Thomas, PhD; Fan Li, PhD; Michael J. Pencina, PhD. JAMA. Original Investigation. Association of ACEI or ARB Use With COVID-19 Diagnosis and Mortality. Hindricks G , Potpara T , Dagres N , et al; ESC Scientific Document Group. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special ... JAMA Cardiology ’s impact factor was 30.2 in 2022 (which is reported for 2021). The journal’s weekly online content is now delivered to more than 97 000 readers, with 3.3 million annual article views and downloads. We maintain an active presence on social media, with an increase during the past year to more than 114 000 Twitter and Facebook ... 4 Associate Editor, JAMA Cardiology. 5 Duke University School of Medicine, Durham, North Carolina. 6 Deputy Editor for Statistics, JAMA Cardiology. 7 Department of Pharmacological and Biomolecular Sciences, University of …Importance Limited evidence suggests exercise reduces blood pressure (BP) in individuals with resistant hypertension, a clinical population with low responsiveness to drug therapy.. Objective To determine whether an aerobic exercise training intervention reduces ambulatory BP among patients with resistant hypertension.. Design, Settings, and … This secondary analysis of a randomized clinical trial examines whether longitudinal increases in high-sensitivity C-reactive protein levels during 16 weeks after an acute coronary syndrome are associated with increased risk of a major adverse cardiac event, cardiovascular death, and all-cause... Introduction. In rural and regional settings, reperfusion therapy for ST-segment elevation myocardial infarction (STEMI) involves thrombolysis followed by transfer to a percutaneous coronary intervention (PCI)–capable hospital. 1, 2 Rapid and correct diagnosis is the first step in the chain of survival for patients with STEMI.JAMA Network is a consortium of peer-reviewed medical publications that includes JAMA® and the JAMA Network journals. JAMA Cardiology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the ...JAMA Cardiology is an international peer-reviewed journal and the definitive journal for clinical investigators, clinicians, and trainees in cardiovascular medicine …

JAMA Cardiology. Editor's Comment. A Brief Window to Rethink Emergency Care. Melinda B. Buntin, PhD. JAMA Health Forum. We are in the midst of the coronavirus disease 2019 (COVID-19) pandemic and, as many clinicians across the globe, we are seeing firsthand the pain and death caused by COVID-19.

Key Points. Question What is the temporal association between episodes of atrial fibrillation (AF) and ischemic stroke in patients with cardiac implantable electronic devices (CIEDs)?. Findings In this case-crossover study including 891 patients with CIEDs and ischemic stroke, multihour AF episodes raised the odds of stroke 3.7-fold for up to 30 days.

MeaningRestrictions on trans-fatty acid consumption are associated with a decrease in hospitalization for cardiovascular events. ImportanceTrans-fatty acids (TFAs) have deleterious cardiovascular effects. Restrictions on their use were initiated in 11 New York State (NYS) counties between 2007 and 2011.Beyond this recommendation, however, some investigators have called for broader de-risking of patients with a CAC score of 0, suggesting that even those with familial hypercholesterolemia and a CAC score of 0 may not need add-on therapy beyond statins and ezetimibe. 7 The article by Mortensen et al 8 in this issue of JAMA Cardiology …This analysis of pooled data from 2 randomized clinical trials evaluates the 5-year incidence, clinical outcomes, and predictors of hemodynamic structural valve deterioration in patients undergoing self-expanding transcatheter aortic valve implantation or surgery.In this issue of JAMA Cardiology, Lindner and colleagues 4 report on 39 autopsy cases of patients with COVID-19 in whom pneumonia was the clinical cause of death in 35 of 39 (89.7%). While histopathologic evaluation did not meet criteria seen in acute myocarditis, ...Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. 2009;301 (22):2331-2339. PubMed Google Scholar. Clarke R, Peden JF, Hopewell JC, et al; PROCARDIS Consortium. Genetic variants associated with Lp (a) lipoprotein level and coronary disease. N Engl J Med. 2009;361 (26):2518-2528.Key Points. Question Can targeted use of a polygenic risk score (PRS) for coronary artery disease (CAD) have clinical utility in the decision to initiate statin therapy for primary prevention?. Findings In this cohort study of 330 201 patients, a PRS for CAD carried significantly greater predictive power in younger adults, contributing up to 30% of … JAMA Cardiology ’s impact factor was 30.2 in 2022 (which is reported for 2021). The journal’s weekly online content is now delivered to more than 97 000 readers, with 3.3 million annual article views and downloads. We maintain an active presence on social media, with an increase during the past year to more than 114 000 Twitter and Facebook ... Key Points. Question Can severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) be documented in cardiac tissue of coronavirus disease 2019 (COVID-19) autopsy cases?. …Key Points. Question What is the diagnostic and prognostic value of stress cardiovascular magnetic resonance imaging (CMR) for the evaluation of stable chest pain?. Findings In this systematic review and meta-analysis pooling 74 470 patients with stable chest pain over 381 357 person-years of follow-up, stress CMR yielded high diagnostic accuracy and …Smoothed conditional mean plots visualizing the variation of incidence rates of myocardial infarction with 95% CI by different weather parameters. Unadjusted and adjusted incidence rate ratio (IRR) and 95% CI from regression analyses are presented with each graph. Results from the regression analyses are interpreted as change per increase in ...

van Diepen S, Fordyce CB, Wegermann ZK, et al. Organizational structure, staffing, resources, and educational initiatives in cardiac intensive care units in the United States: an American Heart Association Acute Cardiac Care Committee and American College of Cardiology Critical care Cardiology Working Group cross sectional survey. A, Composite outcome, B, all-cause mortality, and C, major cardiovascular disease (CVD) adjusted for age, sex, urban or rural residence, country income level, education level, household wealth index, smoking status, physical activity, depression, baseline chronic diseases, physical impairments, and a random intercept for clustering of centers. Jan 1, 2021 · Myocarditis is a significant cause of sudden cardiac death in competitive athletes and can occur with normal ventricular function. 1 Recent studies have raised concerns of myocardial inflammation after recovery from coronavirus disease 2019 (COVID-19), even in asymptomatic or mildly symptomatic patients. 2 Our objective was to investigate the use of cardiac magnetic resonance (CMR) imaging in ... Instagram:https://instagram. friends experiencebarahona expresselliott supply companybananarama roatan JAMA Cardiology. Key Points. Question Is a ticagrelor-based or prasugrel hydrochloride–based strategy superior for patients with acute coronary syndrome treated with percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial, among ... th porn dudelowes nashua Key Points. Question What are the efficacy and safety of omecamtiv mecarbil for the treatment of patients with severe heart failure (HF)?. Finding In this post hoc analysis of data from 8232 patients with symptomatic HF enrolled in the Global Approach to Lowering Adverse Cardiac Outcomes Through Improving Contractility in Heart Failure …JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) avanti destinations Jul 1, 2020 · JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Jan 14, 2021 · Thirty of 789 athletes (3.8%) had abnormal cardiac screening test results necessitating additional evaluation and downstream testing; 5 athletes (0.6%) were detected to have findings raising concern for COVID-19–associated inflammatory heart disease that resulted in restriction from sport participation per American Heart Association (AHA)/American College of Cardiology (ACC) guidelines. 10 ...